منابع مشابه
An NMR approach to structural proteomics.
The influx of genomic sequence information has led to the concept of structural proteomics, the determination of protein structures on a genome-wide scale. Here we describe an approach to structural proteomics of small proteins using NMR spectroscopy. Over 500 small proteins from several organisms were cloned, expressed, purified, and evaluated by NMR. Although there was variability among prote...
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Nuclear magnetic resonance (NMR) is a powerful spectroscopic technique that permits the detailed study at atomic resolution of the three-dimensional structure and dynamics of macromolecules and their complexes in solution. In this brief chapter, I discuss various aspects of NMR that are pertinent to structural proteomics, that is, the high-throughput study of protein–protein complexes at the at...
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This paper describes the developments, role and contributions of the NMR spectroscopy groups in the Structural Proteomics In Europe (SPINE) consortium. Focusing on the development of high-throughput (HTP) pipelines for NMR structure determinations of proteins, all aspects from sample preparation, data acquisition, data processing, data analysis to structure determination have been improved with...
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Spatial planning approaches along with complication of societies are being changed. These changes and transformations have reflected themselves in increasing diversification of economic patterns, people, group, organization, and institution’s mobility. While in less developed network societies some of the concepts including “distance” and “movement “are relatively losing their importance , some...
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the aim of this study has been to find answers for the following questions: 1. what is the effect of immediate correction on students pronunciation errors? 2. what would be the effect of teaching the more rgular patterns of english pronunciation? 3. is there any significant difference between the two methods of dealing with pronuciation errore, i. e., correction and the teaching of the regular ...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2002
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.042684599